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02162 康諾亞生物
Keymed Biosciences
Listing Date2021/07/08
Listing Price53.300
  • 40.700 -2.300 (-5.349%)    Sink Below Listing Price
  • 15-min delayed, last update: 21/10/2021 17:59
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Keymed Biosciences is a biotechnology company. It primarily focuses on the in-house discovery and development of innovative biological therapies in the autoimmune and oncology therapeutic areas.

Its Core Product, CM310, is a highly potent antagonist antibody against interleukin-4 receptor -subunit (IL-4R), intended to treat various allergic diseases, such as moderate-to-severe atopic dermatitis (AD), moderate-to-severe eosinophilic asthma and chronic rhinosinusitis with nasal polyposis (CRSwNP), and potentially chronic obstructive pulmonary disease (COPD).

The five clinical-stage drug candidates, each among the first three domestically-developed for its target or in its class to have obtained investigational new drug (IND) approval in China and/or the U.S. All of 33 patent applications were pending, including 16 patent applications in China, two patent applications in the U.S., seven patent applications under the Patent Cooperation Treaty and eight patent applications in other jurisdictions, relating to certain of drug candidates and technologies. Specifically, in relation to its Core Product, CM310.

The Group entered into an exclusive license agreement with CSPC Pharmaceutical Group Limited (01093) to develop and commercialize CM310 for the treatment of moderate and severe asthma, COPD and other respiratory diseases in China.

MarketHong Kong (Main Board)
Business NatureHealth Care
Major Business AreaChina
Board Lot500
No. of Offer Shares58.26m shares
No. of International Offer Shares52.44m shares
No. of HK Offer Shares5.83m shares
Offer Price$50.50 - $53.30
Registrar & Transfer OfficeComputershare Hong Kong Investor Services
Stock Code2162
Sponsor(s)Morgan Stanley Asia Limited; China International Capital Corporation Hong Kong Securities Limited; Huatai Financial Holdings (Hong Kong) Limited
Underwriter(s)Morgan Stanley Asia Limited; China International Capital Corporation Hong Kong Securities Limited; Huatai Financial Holdings (Hong Kong) Limited; China Everbright Securities (HK) Limited
Application PeriodJun 25 (Fri) - Noon, Jun 30 (Wed)
Price Determination DateOn or Before 5pm, Jun 30 (Wed)
Result Announcement DateOn or Before Jul 7 (Wed)
Dispatch of Shares and Refund ChequesOn or Before Jul 7 (Wed)
Dealings in Shares commence onJul 8, 2021. (Thu)
Reallocation of Shares Offered
Times of HK Offer Shares Subscription15X - 50X50X - 100XOver 100X
% of total shares reallocated to HK Offer30%40%50%
ExecutiveBo CHEN (Chairman), Changyu WANG, Gang XU
Non-ExecutiveQi CHEN, Dong LYU, Min Chuan WANG, Yilun LIU
Independent Non-ExecutiveXiao-Fan WANG, Yang KE, Cheuk Kin Stephen LAW, Linqing LIU
Director Bo CHEN and related parties35.35%
Hillhouse Capital10.39%
(Year ended Dec 31)
Pre-Taxed Profit(818,848)(167,512)--
Attributable Profit for the period(818,583)(167,512)--
Offer Price$50.50 - $53.30
Capitalization$13,685m - $14,444m
Unaudited pro forma adj NAV / share$14.26 - $14.97
Assuming the offer price being at the mid-point of $51.90, the net proceeds raised would be HK$2,863.8m, of which:
* $1,718.3m (60.0%) to R&D and commercialization of following Core Product ;
* $429.6m (15.0%) to preclinical evaluation and clinical development of our other pipeline drug candidates products ;
* $429.6m (15.0%) to payment of lease for new manufacturing and R&D facilities; and
* the balance of $286.4m (10.0%) as additional working capital.
Code Name Nominal Change %Change
01801INNOVENT BIOdown76.900-0.400-0.517%
01877JUNSHI BIOdown41.050-0.800-1.912%
01952EVEREST MED-Bup44.0000.8501.970%
02096SIMCERE PHARMAup7.9500.0600.760%
02142HBM HOLDINGS-Bdown6.420-0.080-1.231%
02162KEYMED BIO-Bdown40.700-2.300-5.349%
02607SH PHARMAdown15.000-0.280-1.832%
02616CSTONE PHARMA-Bdown9.780-0.300-2.976%
09688ZAI LAB-SBdown767.500-23.000-2.910%
15-min delayed, last updated: 21/10/2021 17:59
Related Document
Remark: The above information is referenced from the prospectus.
  All data is calculated from the non- exercise rights(if applicable).
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